Endogenous microRNAs in human microvascular endothelial cells regulate mRNAs encoded by hypertension-related genes Kriegel and Colleagues, Hypertension 2015 Identification of 35 miRNA-target pairs relevant to hypertension. To read more click here.
Base-resolution maps of 5-methylcytosine and 5-hydroxymethylcytosine in Dahl S rats: effect of salt and genomic sequence Liang and Colleagues, Hypertension. 2014
Anne Temple2021-06-10T15:04:26+00:00Base-resolution maps of 5-methylcytosine and 5-hydroxymethylcytosine in Dahl S rats: effect of salt and genomic sequence Liang and Colleagues, Hypertension 2014 One of the first base-resolution maps of 5mC and 5hmC in an in-vivo disease setting. To read more click here.
Efficient Precision Genome Editing in iPSCs via Genetic Co-targeting with Selection Geurts and Colleagues, Stem Cell Reports, 2017
Anne Temple2021-06-10T15:02:14+00:00Efficient Precision Genome Editing in iPSCs via Genetic Co-targeting with Selection Geurts and Colleagues, Stem Cell Reports 2017 The potential of CRISPR/Cas9-based genome editing in iPSCs is currently hampered by the laborious nature of identifying cells modified by low frequency homology-directed repair (HDR) pathway. The Geurts lab presents a straightforward approach, termed co-targeting [...]